Opened in 1987, the Appleton is located in Central Florida and is home to an extraordinary permanent collection of over 24,000 objects, plus an outdoor sculpture walk and garden, and a wide variety of temporary exhibitions and special events throughout the year.

The 81,610 square-foot museum is both classical and contemporary, with clean lines and stately Italian travertine marble. The original building surrounds an idyllic interior courtyard and fountain.

The Appleton is the focal point of the Appleton Cultural Center, a complex east of downtown Ocala on Silver Springs Blvd./State Road 40, which includes the Ocala Civic Theatre, and is one of six College of Central Florida campuses.